EXO1

Across TCGA patient cohorts, EXO1 protein abundance is significantly associated with the RNA expression of many other genes, with 317 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible EXO1-associated genes across cancer lineages are DHCR24, PPP2CB, and ICAM5. Each is linked with EXO1 in more than 1 cancer types. Because this analysis shows association rather than direction, both EXO1-to-partner and partner-to-EXO1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EXO1 versus DHCR24 in BRCA, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EXO1→partner) and Y-score (partner→EXO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DHCR24 →	-1.298	-0.392	<.001	.001	3	2
LSCC	PPP2CB →	-0.505	-0.701	<.001	.007	3	1
LSCC	ICAM5 →	-0.562	-0.989	.005	.005	3	1
LSCC	WLS →	-1.006	-0.784	<.001	.002	3	1
LSCC	RRAS →	-0.763	-0.709	.001	.007	3	1
LSCC	ATP8B3 →	-0.823	-1.032	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 317 associations by consensus.

EXO1 vs DHCR24 — BRCA

Explore this scatter interactively →