Across TCGA patient cohorts, EXD3 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,743 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible EXD3-associated proteins across cancer lineages are PDIA6, PTPA, and BSPRY. Each is linked with EXD3 in more than 5 cancer types. Because this analysis shows association rather than direction, both EXD3-to-partner and partner-to-EXD3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EXD3→partner) and Y-score (partner→EXD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PDIA6 →	-0.338	-0.487	<.001	<.001	3	6
GBM	PTPA →	+0.333	+0.517	<.001	<.001	3	6
LSCC	BSPRY →	+0.675	+0.542	<.001	<.001	3	6
LSCC	FKBP11 →	-0.620	-0.538	<.001	<.001	3	6
GBM	HSP90B1 →	-0.359	-0.516	<.001	<.001	3	6
CCRCC	SLC38A1_S52 →	-0.761	-0.626	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,743 associations by consensus.

Exploration

EXD3 survival (RNA) · tumor vs normal (RNA) · all EXD3 data types