Across TCGA patient cohorts, EXD3 mutation is significantly associated with the RNA expression of many other genes, with 3,010 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EXD3-associated genes across cancer lineages are MIR6803, SNORD37, and BMS1P19. Each is linked with EXD3 in more than 2 cancer types. Because this analysis shows association rather than direction, both EXD3-to-partner and partner-to-EXD3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EXD3→partner) and Y-score (partner→EXD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6803 →	+0.090	+3.671	<.001	.008	3	3
CESC	SNORD37 →	+0.668	+3.714	.006	.006	3	2
CESC	BMS1P19 →	+0.095	+3.542	.002	.007	3	2
COAD	WNT4 →	-0.902	-2.906	<.001	.001	3	2
UCEC	CCDC74A →	-0.700	-1.978	.002	.001	3	2
UCEC	MRPS18C →	+0.298	+1.914	.005	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,010 associations by consensus.

Exploration

EXD3 survival (RNA) · tumor vs normal (RNA) · all EXD3 data types