EXD2

Across TCGA cell cohorts, EXD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,236 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible EXD2-associated GO terms across cancer lineages are Protein catabolic process at synapse, Protein catabolic process at postsynapse, and Vesicle tethering. Each is linked with EXD2 in more than 14 cancer types. Because this analysis shows association rather than direction, both EXD2-to-partner and partner-to-EXD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein catabolic process at synapse grouped by EXD2-low versus EXD2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EXD2→partner) and Y-score (partner→EXD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Protein catabolic process at synapse →	+0.174	+0.990	<.001	.001	2	15
URINARY_TRACT	Protein catabolic process at postsynapse →	+0.174	+0.990	<.001	.001	2	15
LUNG_SCLC	Vesicle tethering →	+0.088	+0.784	<.001	.001	3	13
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.168	+1.177	<.001	.002	3	13
OESOPHAGUS	Regulation of syncytium formation by plasma membrane fusion →	+0.149	+1.114	<.001	.005	3	13
OESOPHAGUS	Golgi vesicle transport →	+0.069	+0.796	.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,236 associations by consensus.

Protein catabolic process at synapse by EXD2 expression — URINARY_TRACT

Explore this box plot interactively →