EXD1

Across TCGA cell cohorts, EXD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,840 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible EXD1-associated GO terms across cancer lineages are Positive regulation of monoatomic ion transmembrane transport, Actin-mediated cell contraction, and Negative regulation of cation transmembrane transport. Each is linked with EXD1 in more than 7 cancer types. Because this analysis shows association rather than direction, both EXD1-to-partner and partner-to-EXD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of monoatomic ion transmembrane transport grouped by EXD1-low versus EXD1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EXD1→partner) and Y-score (partner→EXD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Positive regulation of monoatomic ion transmembrane transport →	-0.095	-0.093	.002	.007	3	8
LUNG_SCLC	Actin-mediated cell contraction →	-0.082	-0.279	.001	<.001	3	8
LUNG_SCLC	Negative regulation of cation transmembrane transport →	-0.105	-0.233	.008	.009	3	7
LUNG_NSCLC_LUAD	Actin filament-based movement →	-0.077	-0.196	.001	.001	3	7
LUNG_NSCLC_LUSC	Zinc ion import into lysosome →	-0.323	-0.207	.001	.001	3	6
LIVER	Positive regulation of translation →	+0.087	+0.249	.002	.009	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,840 associations by consensus.

Positive regulation of monoatomic ion transmembrane transport by EXD1 expression — STOMACH

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