EWSR1

Across TCGA patient cohorts, EWSR1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,160 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EWSR1-associated genes across cancer lineages are TXN2, EIF3D, and XRCC6. Each is linked with EWSR1 in more than 4 cancer types. Because this analysis shows association rather than direction, both EWSR1-to-partner and partner-to-EWSR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EWSR1 versus TXN2 in OV, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EWSR1→partner) and Y-score (partner→EWSR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TXN2 →	+0.499	+0.393	<.001	<.001	3	5
OV	EIF3D →	+0.708	+0.413	<.001	<.001	3	5
UCEC	XRCC6 →	+0.654	+0.134	.006	.003	3	5
GBM	DANCR →	+0.958	+0.336	<.001	<.001	3	4
LSCC	TUG1 →	+0.501	+0.205	<.001	<.001	3	4
LSCC	TOMM22 →	+0.581	+0.214	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,160 associations by consensus.

EWSR1 vs TXN2 — OV

Explore this scatter interactively →