EVX2

Across TCGA patient cohorts, EVX2 mutation is significantly associated with the RNA expression of many other genes, with 439 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EVX2-associated genes across cancer lineages are RNU6-340P, MIR4747, and MIR3619. Each is linked with EVX2 in more than 2 cancer types. Because this analysis shows association rather than direction, both EVX2-to-partner and partner-to-EVX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-340P grouped by EVX2-low versus EVX2-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EVX2→partner) and Y-score (partner→EVX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU6-340P →	+0.319	+4.847	<.001	<.001	3	3
SKCM	MIR4747 →	+0.411	+4.887	<.001	<.001	3	3
LIHC	MIR3619 →	+0.433	+5.108	<.001	.008	3	2
LUAD	RRAGAP1 →	+0.115	+3.043	<.001	.006	3	2
LUAD	MIR3713 →	+0.419	+3.480	.008	.005	3	2
SKCM	RN7SL383P →	+0.059	+5.225	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 439 associations by consensus.

RNU6-340P by EVX2 expression — LUAD

Explore this box plot interactively →