EVX2

Across TCGA cell cohorts, EVX2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,415 significant associations in total. BONE shows the largest number of these associations.

The most reproducible EVX2-associated GO terms across cancer lineages are Positive regulation of termination of RNA polymerase II transcription, Positive regulation of termination of DNA-templated transcription, and Transcription initiation at RNA polymerase II promoter. Each is linked with EVX2 in more than 5 cancer types. Because this analysis shows association rather than direction, both EVX2-to-partner and partner-to-EVX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of termination of RNA polymerase II transcription grouped by EVX2-low versus EVX2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EVX2→partner) and Y-score (partner→EVX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of termination of RNA polymerase II transcription →	+0.114	+0.986	.001	.006	3	6
BONE	Positive regulation of termination of DNA-templated transcription →	+0.114	+0.986	.001	.006	3	6
BONE	Transcription initiation at RNA polymerase II promoter →	+0.056	+0.702	.001	.009	3	6
SKIN	Protein-RNA complex assembly →	+0.042	+0.034	<.001	.009	3	6
LUNG_SCLC	mRNA transport →	+0.093	+0.308	.002	.008	3	5
SKIN	Positive regulation of ERK1 and ERK2 cascade →	-0.051	-0.029	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,415 associations by consensus.

Positive regulation of termination of RNA polymerase II transcription by EVX2 expression — BONE

Explore this box plot interactively →