EVX2

Across TCGA cell cohorts, EVX2 mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EVX2-associated genes across cancer lineages are SKOR2, PRAMEF4, and OR8J2. Each is linked with EVX2 in more than 1 cancer types. Because this analysis shows association rather than direction, both EVX2-to-partner and partner-to-EVX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SKOR2 grouped by EVX2-low versus EVX2-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EVX2→partner) and Y-score (partner→EVX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	SKOR2 →	+0.023	+5.285	<.001	.003	3	1
STOMACH	PRAMEF4 →	+0.006	+5.285	<.001	.003	3	1
SKIN	OR8J2 →	+0.076	+4.095	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR13C4 →	+0.011	+3.150	<.001	.006	3	1
LUNG_NSCLC_LUAD	C2orf73 →	+0.090	+3.515	.005	.004	3	1
LUNG_NSCLC_LUAD	MRGPRG →	+0.019	+2.959	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

SKOR2 by EVX2 expression — STOMACH

Explore this box plot interactively →