EVX1

Across TCGA patient cohorts, EVX1 mutation is significantly associated with the RNA expression of many other genes, with 1,420 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EVX1-associated genes across cancer lineages are FBXO3-DT, RNA5SP237, and MIR7853. Each is linked with EVX1 in more than 1 cancer types. Because this analysis shows association rather than direction, both EVX1-to-partner and partner-to-EVX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FBXO3-DT grouped by EVX1-low versus EVX1-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EVX1→partner) and Y-score (partner→EVX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	FBXO3-DT →	+0.139	+4.241	<.001	.003	3	2
BLCA	RNA5SP237 →	+0.219	+4.588	.005	.008	3	2
ESCA	MIR7853 →	+0.331	+5.247	<.001	.006	3	1
SKCM	RNA5SP456 →	+0.186	+4.328	<.001	.007	3	1
SKCM	MIR191 →	+0.245	+3.817	<.001	.004	3	1
SKCM	TRAJ45 →	+0.547	+3.356	.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,420 associations by consensus.

FBXO3-DT by EVX1 expression — LUAD

Explore this box plot interactively →