EVX1

Across TCGA cell cohorts, EVX1 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible EVX1-associated genes across cancer lineages are FAM9A, BPIFB6, and CFC1B. Each is linked with EVX1 in more than 1 cancer types. Because this analysis shows association rather than direction, both EVX1-to-partner and partner-to-EVX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM9A grouped by EVX1-low versus EVX1-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EVX1→partner) and Y-score (partner→EVX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	FAM9A →	+0.049	+5.169	<.001	.005	3	1
BLOOD_Leukemia	BPIFB6 →	+0.047	+4.969	<.001	.003	3	1
SKIN	CFC1B →	+0.070	+6.022	<.001	.001	3	1
SKIN	SPATA31D4 →	+0.205	+4.977	<.001	.007	3	1
SKIN	OR13C3 →	+0.030	+6.022	<.001	.001	3	1
SKIN	OR1D5 →	+0.023	+6.022	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

FAM9A by EVX1 expression — BREAST

Explore this box plot interactively →