Across TCGA patient cohorts, EVPLL mutation is significantly associated with the RNA expression of many other genes, with 551 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EVPLL-associated genes across cancer lineages are MTND5P35, SNORD37, and UQCRBP3. Each is linked with EVPLL in more than 1 cancer types. Because this analysis shows association rather than direction, both EVPLL-to-partner and partner-to-EVPLL results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EVPLL→partner) and Y-score (partner→EVPLL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MTND5P35 →	+0.061	+5.984	<.001	.002	3	2
UCEC	SNORD37 →	+0.575	+2.199	.001	.006	3	2
UCEC	UQCRBP3 →	+0.166	+2.911	<.001	.003	3	2
SKCM	BMS1P3 →	+0.036	+4.469	<.001	.006	3	2
SKCM	DDX3P3 →	+0.030	+3.427	<.001	.006	3	2
SKCM	RNA5SP519 →	+0.271	+4.513	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 551 associations by consensus.

Exploration

EVPLL survival (RNA) · tumor vs normal (RNA) · all EVPLL data types