Across TCGA patient cohorts, EVL mutation is significantly associated with the total protein of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EVL-associated genes across cancer lineages are 4E-BP1, 14-3-3_beta, and MEK1. Each is linked with EVL in more than 2 cancer types. Because this analysis shows association rather than direction, both EVL-to-partner and partner-to-EVL results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EVL→partner) and Y-score (partner→EVL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	4E-BP1 →	+0.271	+2.837	.022	.035	2	3
UCEC	14-3-3_beta →	-0.104	-2.102	.017	.019	3	1
UCEC	MEK1 →	+0.484	+3.584	.002	.002	3	1
UCEC	MSH2 →	-0.304	-3.143	.002	.018	3	1
UCEC	MSH6 →	-0.425	-3.169	.003	.018	3	1
UCEC	PDCD4 →	-0.563	-3.321	.006	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

EVL survival (RNA) · tumor vs normal (RNA) · all EVL data types