EVI5

Across TCGA patient cohorts, EVI5 protein abundance is significantly associated with the RNA expression of many other genes, with 9,503 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EVI5-associated genes across cancer lineages are SH2D3C, SRPX, and CPED1. Each is linked with EVI5 in more than 3 cancer types. Because this analysis shows association rather than direction, both EVI5-to-partner and partner-to-EVI5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EVI5 versus SH2D3C in OV, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EVI5→partner) and Y-score (partner→EVI5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SH2D3C →	+0.478	+0.393	.006	.005	3	4
LSCC	SRPX →	+0.990	+0.227	<.001	<.001	3	4
BRCA	CPED1 →	+0.820	+0.217	<.001	.001	3	4
CCRCC	DCN →	+1.235	+0.148	<.001	.002	3	4
UCEC	PLPPR4 →	+0.849	+0.204	.003	.006	3	4
CCRCC	PPFIA2 →	+0.541	+0.190	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,503 associations by consensus.

EVI5 vs SH2D3C — OV

Explore this scatter interactively →