Across TCGA patient cohorts, EVI2B mutation is significantly associated with the RNA expression of many other genes, with 141 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EVI2B-associated genes across cancer lineages are RPS29P32, RNA5SP136, and SNRPGP17. Each is linked with EVI2B in more than 1 cancer types. Because this analysis shows association rather than direction, both EVI2B-to-partner and partner-to-EVI2B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EVI2B→partner) and Y-score (partner→EVI2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPS29P32 →	+0.715	+3.014	<.001	.004	3	2
UCEC	RNA5SP136 →	+0.393	+3.077	<.001	.009	3	2
UCEC	SNRPGP17 →	+0.286	+2.463	.007	.008	3	1
UCEC	MIR6821 →	+0.505	+2.967	<.001	.002	3	1
UCEC	FLCN →	+0.641	+3.218	<.001	.009	3	1
UCEC	SEPTIN14 →	+0.747	+2.797	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 141 associations by consensus.

Exploration

EVI2B survival (RNA) · tumor vs normal (RNA) · all EVI2B data types