EVC2

Across TCGA pan-cancer cohorts, EVC2 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated EVC2 data layer compared with 26 for mass-spec protein and 9 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher EVC2 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated EVC2 expression acts as an unfavorable survival marker, although some lineages such as GBM and HNSC show a favorable association.

GBM and HNSC are the cancer types where EVC2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	DFS	Quartile	All	0.782	0.410	.026	3	view →
HNSC	OS	Quartile	All	0.921	0.729	.040	2	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

EVC2–GBM (DFS)

Open the GBM breakdown →