EVC2

Across TCGA cell cohorts, EVC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,175 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible EVC2-associated GO terms across cancer lineages are RNA splicing, via transesterification reactions with bulged adenosine as nucleophile, mRNA splicing, via spliceosome, and Myoblast migration involved in skeletal muscle regeneration. Each is linked with EVC2 in more than 6 cancer types. Because this analysis shows association rather than direction, both EVC2-to-partner and partner-to-EVC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA splicing, via transesterification reactions with bulged adenosine as nucleophile grouped by EVC2-low versus EVC2-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EVC2→partner) and Y-score (partner→EVC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile →	+0.058	+0.923	<.001	.004	3	7
SOFT_TISSUE	mRNA splicing, via spliceosome →	+0.058	+0.923	<.001	.004	3	7
BLOOD_Lymphoma	Myoblast migration involved in skeletal muscle regeneration →	+0.152	+0.878	.001	.001	3	7
OVARY	Positive regulation of response to oxidative stress →	+0.133	+0.747	<.001	<.001	3	7
LUNG_NSCLC_LUSC	Golgi to plasma membrane transport →	+0.065	+1.047	.009	.006	3	6
BREAST	Maintenance of protein location in nucleus →	+0.088	+0.823	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,175 associations by consensus.

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile by EVC2 expression — SOFT_TISSUE

Explore this box plot interactively →