EVA1C

Across TCGA cell cohorts, EVA1C mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EVA1C-associated genes across cancer lineages are P2RY12, CD300H, and OR2AP1. Each is linked with EVA1C in more than 1 cancer types. Because this analysis shows association rather than direction, both EVA1C-to-partner and partner-to-EVA1C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, P2RY12 grouped by EVA1C-low versus EVA1C-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EVA1C→partner) and Y-score (partner→EVA1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	P2RY12 →	+0.236	+4.273	<.001	.006	3	1
LARGE_INTESTINE	CD300H →	+0.055	+6.000	<.001	<.001	3	1
BLOOD_Leukemia	OR2AP1 →	+0.009	+4.539	<.001	.007	3	1
BLOOD_Leukemia	ACSM6 →	+0.028	+4.087	<.001	.009	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

P2RY12 by EVA1C expression — LARGE_INTESTINE

Explore this box plot interactively →