Across TCGA pan-cancer cohorts, EVA1B mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated EVA1B data layer compared with 24 for mass-spec protein and 4 for mutation status.
The strongest signal is observed in lung adenocarcinoma (LUAD), where higher EVA1B mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated EVA1B expression acts as an unfavorable survival marker, although some lineages such as LUAD and PDAC show a favorable association.
LUAD, PDAC, and LSCC are the cancer types where EVA1B mass-spec protein most reproducibly stratifies survival.