EVA1B

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, EVA1B mutation is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible EVA1B-associated genes across cancer lineages are RNU6-1210P, YRDCP3, and MORC1-AS1. Each is linked with EVA1B in more than 1 cancer types. Because this analysis shows association rather than direction, both EVA1B-to-partner and partner-to-EVA1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1210P grouped by EVA1B-low versus EVA1B-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EVA1B→partner) and Y-score (partner→EVA1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADRNU6-1210P →+0.553+7.741<.001.00931
COADYRDCP3 →+0.161+7.741<.001.00931
COADMORC1-AS1 →+0.142+7.741.001.00931
COADRN7SKP122 →+0.252+7.741<.001.00931
COADRNU6-165P →+0.587+7.741<.001.00931
COADRNU6-889P →+0.569+7.741<.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

RNU6-1210P by EVA1B expression — COAD

Box plot of RNU6-1210P in EVA1B-low vs EVA1B-high samples in COAD.

Explore this box plot interactively →

Exploration