EVA1A

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, EVA1A protein abundance is significantly associated with the RNA expression of many other genes, with 2,006 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EVA1A-associated genes across cancer lineages are ELFN2, H3P36, and SPOCD1. Each is linked with EVA1A in more than 2 cancer types. Because this analysis shows association rather than direction, both EVA1A-to-partner and partner-to-EVA1A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EVA1A versus ELFN2 in CCRCC, with a Pearson correlation of 0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EVA1A→partner) and Y-score (partner→EVA1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CCRCCELFN2 →+1.216+0.547.002.00533
UCECH3P36 →-1.496-1.162.001<.00132
LSCCSPOCD1 →+1.805+0.982<.001.00532
LSCCPYROXD2 →+0.777+0.628.007.00632
LSCCNT5E →+2.312+0.912.001.00532
LSCCFHOD1 →+0.990+0.890.002.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,006 associations by consensus.

EVA1A vs ELFN2 — CCRCC

Per-sample scatter of EVA1A vs ELFN2 in CCRCC (Pearson r = 0.59).

Explore this scatter interactively →

Exploration