EVA1A

Across TCGA patient cohorts, EVA1A mutation is significantly associated with the RNA expression of many other genes, with 2,017 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EVA1A-associated genes across cancer lineages are TRIM64DP, MIR4444-2, and MIR1273C. Each is linked with EVA1A in more than 1 cancer types. Because this analysis shows association rather than direction, both EVA1A-to-partner and partner-to-EVA1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRIM64DP grouped by EVA1A-low versus EVA1A-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EVA1A→partner) and Y-score (partner→EVA1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	TRIM64DP →	+0.081	+5.797	<.001	.001	3	2
SKCM	MIR4444-2 →	+0.517	+4.470	.001	.005	3	2
HNSC	MIR1273C →	+0.512	+3.945	.007	.003	3	2
COAD	MTND4P1 →	+0.194	+5.790	<.001	.003	3	2
COAD	SLC20A1P3 →	+0.125	+6.917	<.001	<.001	3	2
SKCM	MTND2P18 →	+0.055	+6.452	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,017 associations by consensus.

TRIM64DP by EVA1A expression — SKCM

Explore this box plot interactively →