EVA1A

Across TCGA cell cohorts, EVA1A RNA expression is significantly associated with the go_rna of many other GO terms, with 5,861 significant associations in total. BONE shows the largest number of these associations.

The most reproducible EVA1A-associated GO terms across cancer lineages are Caveola assembly, Positive regulation of cell-substrate junction organization, and Regulation of protein localization to mitochondrion. Each is linked with EVA1A in more than 14 cancer types. Because this analysis shows association rather than direction, both EVA1A-to-partner and partner-to-EVA1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caveola assembly grouped by EVA1A-low versus EVA1A-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EVA1A→partner) and Y-score (partner→EVA1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Caveola assembly →	+0.229	+3.270	<.001	<.001	3	15
BONE	Positive regulation of cell-substrate junction organization →	+0.171	+3.390	<.001	<.001	3	12
STOMACH	Regulation of protein localization to mitochondrion →	+0.115	+3.837	<.001	<.001	3	12
LUNG_NSCLC_LUSC	PML body organization →	+0.213	+2.937	<.001	<.001	3	12
BONE	Positive regulation of actin filament bundle assembly →	+0.162	+3.047	<.001	<.001	3	12
BONE	Negative regulation of Rho protein signal transduction →	+0.179	+3.681	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,861 associations by consensus.

Caveola assembly by EVA1A expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →