ETV6

Across TCGA patient cohorts, ETV6 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,469 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible ETV6-associated proteins across cancer lineages are ETV6_S213, MVB12A_S170, and L2HGDH. Each is linked with ETV6 in more than 6 cancer types. Because this analysis shows association rather than direction, both ETV6-to-partner and partner-to-ETV6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ETV6 versus ETV6_S213 in HNSC, with a Pearson correlation of 0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ETV6→partner) and Y-score (partner→ETV6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ETV6_S213 →	+0.585	+0.687	<.001	<.001	3	7
UCEC	MVB12A_S170 →	-0.621	-0.429	<.001	.003	3	4
LSCC	L2HGDH →	-0.386	-0.580	<.001	.001	3	4
HNSC	LGALSL →	-0.568	-0.561	<.001	<.001	3	4
OV	SH3PXD2B_S291 →	+0.905	+0.663	.009	.004	3	4
BRCA	RAP1GAP2_S507 →	-0.703	-0.572	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,469 associations by consensus.

ETV6 vs ETV6_S213 — HNSC

Explore this scatter interactively →