ETV6

Across TCGA patient cohorts, ETV6 protein abundance is significantly associated with the RNA expression of many other genes, with 14,170 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ETV6-associated genes across cancer lineages are BCL2L14, C1RL, and TAPBPL. Each is linked with ETV6 in more than 4 cancer types. Because this analysis shows association rather than direction, both ETV6-to-partner and partner-to-ETV6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ETV6 versus BCL2L14 in HNSC, with a Pearson correlation of 0.66.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ETV6→partner) and Y-score (partner→ETV6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	BCL2L14 →	+0.653	+0.309	<.001	<.001	3	5
OV	C1RL →	+0.647	+0.241	.006	.008	3	5
OV	TAPBPL →	+0.882	+0.324	<.001	<.001	3	5
LSCC	ING4 →	+0.501	+0.324	.009	.005	2	5
OV	LPCAT3 →	+0.863	+0.431	<.001	<.001	3	4
LSCC	NDUFA9 →	+0.442	+0.376	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,170 associations by consensus.

ETV6 vs BCL2L14 — HNSC

Explore this scatter interactively →