ETV6

Across TCGA cell cohorts, ETV6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,872 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ETV6-associated GO terms across cancer lineages are Cellular response to abiotic stimulus, Cellular response to environmental stimulus, and Positive regulation of leukocyte differentiation. Each is linked with ETV6 in more than 13 cancer types. Because this analysis shows association rather than direction, both ETV6-to-partner and partner-to-ETV6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to abiotic stimulus grouped by ETV6-low versus ETV6-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ETV6→partner) and Y-score (partner→ETV6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Cellular response to abiotic stimulus →	+0.047	+0.924	<.001	<.001	3	14
SKIN	Cellular response to environmental stimulus →	+0.047	+0.924	<.001	<.001	3	14
KIDNEY	Positive regulation of leukocyte differentiation →	+0.081	+1.276	<.001	<.001	3	13
KIDNEY	Positive regulation of hemopoiesis →	+0.081	+1.276	<.001	<.001	3	13
BONE	Small GTPase-mediated signal transduction →	+0.051	+0.803	<.001	<.001	3	12
SOFT_TISSUE	MAPK cascade →	+0.060	+0.873	<.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,872 associations by consensus.

Cellular response to abiotic stimulus by ETV6 expression — SKIN

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