ETV1

Across TCGA patient cohorts, ETV1 mutation is significantly associated with the total protein of many other genes, with 56 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ETV1-associated genes across cancer lineages are ERK2, FoxM1, and TFRC. Each is linked with ETV1 in more than 3 cancer types. Because this analysis shows association rather than direction, both ETV1-to-partner and partner-to-ETV1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ERK2 grouped by ETV1-low versus ETV1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ETV1→partner) and Y-score (partner→ETV1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ERK2 →	+0.138	+1.184	.015	.022	3	4
UCEC	FoxM1 →	+0.199	+1.512	.009	.017	3	3
UCEC	TFRC →	+0.410	+2.115	.009	.016	3	3
UCEC	ASNS →	+0.344	+2.415	.001	.002	3	3
COAD	p90 RSK →	+0.278	+3.178	.031	.010	2	3
UCEC	FASN →	+0.320	+1.999	.006	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 56 associations by consensus.

ERK2 by ETV1 expression — UCEC

Explore this box plot interactively →