ETV1

Across TCGA cell cohorts, ETV1 mutation is significantly associated with the drug of many other genes, with 41 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ETV1-associated genes across cancer lineages are Docetaxel, GW441756, and Doramapimod. Each is linked with ETV1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ETV1-to-partner and partner-to-ETV1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Docetaxel grouped by ETV1-low versus ETV1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ETV1→partner) and Y-score (partner→ETV1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Docetaxel →	+0.605	+2.807	.028	.046	3	1
LARGE_INTESTINE	GW441756 →	+0.382	+2.807	.020	.046	3	1
LARGE_INTESTINE	Doramapimod →	+0.326	+2.807	.028	.046	2	2
LARGE_INTESTINE	MK-1775 →	+0.307	+3.061	.037	.010	3	1
LARGE_INTESTINE	Uprosertib →	+0.573	+2.807	.036	.037	3	1
LARGE_INTESTINE	WZ4003 →	+0.528	+2.807	.004	.037	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

Docetaxel by ETV1 expression — LARGE_INTESTINE

Explore this box plot interactively →