ETS2

Across TCGA patient cohorts, ETS2 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,257 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ETS2-associated proteins across cancer lineages are ITGA1, NID1, and CDK13_S525. Each is linked with ETS2 in more than 5 cancer types. Because this analysis shows association rather than direction, both ETS2-to-partner and partner-to-ETS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ETS2 versus ITGA1 in CCRCC, with a Pearson correlation of 0.57.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ETS2→partner) and Y-score (partner→ETS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	ITGA1 →	+0.507	+0.956	<.001	<.001	3	6
OV	NID1 →	+0.387	+0.565	<.001	.005	3	5
GBM	CDK13_S525 →	-0.363	-0.726	<.001	<.001	3	5
BRCA	AGT →	+0.616	+0.808	<.001	<.001	3	5
BRCA	ITGA6 →	+0.532	+0.888	<.001	<.001	3	5
BRCA	RSU1 →	+0.464	+0.894	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,257 associations by consensus.

ETS2 vs ITGA1 — CCRCC

Explore this scatter interactively →