ETS2

Across TCGA cell cohorts, ETS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,941 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ETS2-associated GO terms across cancer lineages are Intracellular potassium ion homeostasis, Intracellular sodium ion homeostasis, and Negative regulation of response to endoplasmic reticulum stress. Each is linked with ETS2 in more than 8 cancer types. Because this analysis shows association rather than direction, both ETS2-to-partner and partner-to-ETS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intracellular potassium ion homeostasis grouped by ETS2-low versus ETS2-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ETS2→partner) and Y-score (partner→ETS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Intracellular potassium ion homeostasis →	+0.224	+2.301	<.001	<.001	3	9
LARGE_INTESTINE	Intracellular sodium ion homeostasis →	+0.281	+2.251	<.001	<.001	3	9
LUNG_NSCLC_LUAD	Negative regulation of response to endoplasmic reticulum stress →	+0.078	+1.418	<.001	<.001	3	9
STOMACH	Bundle of His cell to Purkinje myocyte communication →	+0.296	+1.365	.001	.006	3	9
LUNG_NSCLC_LUSC	Regulation of sodium ion transmembrane transport →	+0.158	+2.224	.005	.001	3	8
OVARY	Regulation of transforming growth factor beta3 production →	+0.204	+1.946	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,941 associations by consensus.

Intracellular potassium ion homeostasis by ETS2 expression — LARGE_INTESTINE

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