ETS1-AS1

Across TCGA pan-cancer cohorts, ETS1-AS1 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated ETS1-AS1 data layer.

The strongest signal is observed in cholangiocarcinoma (CHOL), where higher ETS1-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ETS1-AS1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and THCA show a favorable association.

CHOL, SKCM, and ACC are the cancer types where ETS1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CHOL	OS	Tertile	All	0.024	0.675	<.001	99	view →
SKCM	DFS	Tertile	IV	0.055	0.515	.005	27	view →
ACC	OS	Tertile	III,IV	0.269	0.787	<.001	27	view →
LUAD	DFS	Tertile	IV	0.047	0.565	<.001	18	view →
ESCA	DFS	Tertile	All	0.417	0.829	.006	17	view →
UCEC	DFS	Tertile	All	0.863	0.904	.016	12	view →
DLBC	DFS	Tertile	III,IV	0.067	0.712	.016	9	view →
MESO	OS	Tertile	III,IV	0.421	0.587	.035	9	view →
READ	DFS	Tertile	II,III,IV	0.184	0.536	.049	6	view →
KIRC	DFS	Median	IV	0.783	0.464	.010	4	view →
LUSC	DFS	Tertile	All	0.265	0.405	.021	3	view →
THCA	DFS	Quartile	All	0.988	0.938	.041	2	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

ETS1-AS1–CHOL (OS)

Open the CHOL breakdown →