ETNK2

Across TCGA patient cohorts, ETNK2 protein abundance is significantly associated with the protein abundance of many other proteins, with 8,143 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ETNK2-associated proteins across cancer lineages are RCSD1_S179, ACSL4, and ACTB. Each is linked with ETNK2 in more than 2 cancer types. Because this analysis shows association rather than direction, both ETNK2-to-partner and partner-to-ETNK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ETNK2 versus RCSD1_S179 in LSCC, with a Pearson correlation of -0.34.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ETNK2→partner) and Y-score (partner→ETNK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RCSD1_S179 →	-0.716	-0.491	.001	.005	3	3
BRCA	ACSL4 →	-0.446	-0.600	<.001	<.001	3	2
LSCC	ACTB →	-0.271	-0.597	<.001	<.001	3	2
BRCA	BPI →	-0.782	-0.356	<.001	<.001	3	2
LSCC	CAP1 →	-0.267	-0.449	<.001	<.001	3	2
BRCA	CGAS →	-0.922	-0.623	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,143 associations by consensus.

ETNK2 vs RCSD1_S179 — LSCC

Explore this scatter interactively →