ETHE1

Across TCGA patient cohorts, ETHE1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,679 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ETHE1-associated proteins across cancer lineages are TIMP1, IRGQ, and TRPM4. Each is linked with ETHE1 in more than 4 cancer types. Because this analysis shows association rather than direction, both ETHE1-to-partner and partner-to-ETHE1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ETHE1 versus TIMP1 in GBM, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ETHE1→partner) and Y-score (partner→ETHE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TIMP1 →	+0.757	+0.231	<.001	.001	3	5
OV	IRGQ →	+0.265	+0.571	.001	<.001	3	5
LSCC	TRPM4 →	+0.405	+0.524	.001	<.001	3	4
BRCA	MYOF →	+0.509	+0.584	<.001	<.001	3	4
HNSC	PPP1R13L →	+0.558	+0.775	<.001	<.001	3	4
LSCC	GATAD2B →	-0.322	-0.473	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,679 associations by consensus.

ETHE1 vs TIMP1 — GBM

Explore this scatter interactively →