ETHE1

Across TCGA patient cohorts, ETHE1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,989 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ETHE1-associated genes across cancer lineages are EME1, CDC6, and PPIL1. Each is linked with ETHE1 in more than 5 cancer types. Because this analysis shows association rather than direction, both ETHE1-to-partner and partner-to-ETHE1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ETHE1 versus EME1 in GBM, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ETHE1→partner) and Y-score (partner→ETHE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	EME1 →	-0.807	-0.396	<.001	<.001	3	6
BRCA	CDC6 →	-0.918	-0.421	<.001	<.001	3	6
HNSC	PPIL1 →	-0.569	-0.205	.006	.004	3	5
GBM	CHEK1 →	-0.961	-0.386	<.001	<.001	3	5
HNSC	TIPIN →	-0.514	-0.256	.007	.005	3	5
LSCC	C3orf33 →	-0.551	-0.375	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,989 associations by consensus.

ETHE1 vs EME1 — GBM

Explore this scatter interactively →