ETHE1

Across TCGA cell cohorts, ETHE1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,975 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ETHE1-associated GO terms across cancer lineages are Hydrogen sulfide metabolic process, Actin filament capping, and Positive regulation of natural killer cell mediated immune response to tumor cell. Each is linked with ETHE1 in more than 12 cancer types. Because this analysis shows association rather than direction, both ETHE1-to-partner and partner-to-ETHE1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Hydrogen sulfide metabolic process grouped by ETHE1-low versus ETHE1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ETHE1→partner) and Y-score (partner→ETHE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Hydrogen sulfide metabolic process →	+0.184	+1.029	.001	.008	3	13
SOFT_TISSUE	Actin filament capping →	+0.194	+1.326	<.001	<.001	3	10
BLOOD_Lymphoma	Positive regulation of natural killer cell mediated immune response to tumor cell →	+1.130	+1.896	<.001	<.001	3	10
BLOOD_Lymphoma	Positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target →	+1.156	+2.006	<.001	<.001	3	10
BREAST	Regulation of plasma cell differentiation →	+0.132	+1.232	<.001	<.001	3	10
URINARY_TRACT	Negative regulation of actin filament polymerization →	+0.149	+0.814	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,975 associations by consensus.

Hydrogen sulfide metabolic process by ETHE1 expression — BONE

Explore this box plot interactively →