Across TCGA pan-cancer cohorts, ETFRF1 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated ETFRF1 data layer compared with 25 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher ETFRF1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ETFRF1 expression acts as an unfavorable survival marker.

OV and LGG are the cancer types where ETFRF1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	OS	Median	II,III,IV	0.082	0.844	<.001	36	view →
LGG	OS	Median	All	0.132	0.811	<.001	12	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: ETFRF1 tumor-vs-normal RNA expression · all ETFRF1 data types