Across TCGA pan-cancer cohorts, ETFRF1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ETFRF1 data layer compared with 25 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher ETFRF1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated ETFRF1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and LSCC show a favorable association.

PDAC, CCRCC, and HNSC are the cancer types where ETFRF1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Tertile	All	0.960	0.596	.002	29	view →
CCRCC	DFS	Quartile	II,III,IV	0.526	0.926	.010	10	view →
HNSC	DFS	Median	II,III,IV	0.878	0.983	.008	10	view →
LSCC	OS	Median	II,III,IV	1.000	0.882	.019	6	view →
LUAD	DFS	Quartile	III,IV	0.277	0.970	.024	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: ETFRF1 tumor-vs-normal RNA expression · all ETFRF1 data types