ETFDH

Across TCGA patient cohorts, ETFDH mutation is significantly associated with the RNA expression of many other genes, with 1,520 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ETFDH-associated genes across cancer lineages are RN7SL544P, SNX3P1Y, and MIR1289-2. Each is linked with ETFDH in more than 1 cancer types. Because this analysis shows association rather than direction, both ETFDH-to-partner and partner-to-ETFDH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL544P grouped by ETFDH-low versus ETFDH-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ETFDH→partner) and Y-score (partner→ETFDH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	RN7SL544P →	+0.136	+5.187	<.001	.007	3	2
UCEC	SNX3P1Y →	+0.062	+3.777	<.001	.007	3	2
LUSC	MIR1289-2 →	+0.457	+4.548	<.001	.009	3	2
LUSC	CTBP2P10 →	+0.058	+6.563	<.001	<.001	3	2
LIHC	OR6R1P →	+0.072	+4.720	<.001	.005	3	2
LIHC	MRPS21P5 →	+0.214	+4.618	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,520 associations by consensus.

RN7SL544P by ETFDH expression — STAD

Explore this box plot interactively →