ETFDH

Across TCGA cell cohorts, ETFDH RNA expression is significantly associated with the go_rna of many other GO terms, with 2,805 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ETFDH-associated GO terms across cancer lineages are Fatty acid beta-oxidation using acyl-CoA dehydrogenase, Lipid oxidation, and Vesicle tethering. Each is linked with ETFDH in more than 12 cancer types. Because this analysis shows association rather than direction, both ETFDH-to-partner and partner-to-ETFDH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Fatty acid beta-oxidation using acyl-CoA dehydrogenase grouped by ETFDH-low versus ETFDH-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ETFDH→partner) and Y-score (partner→ETFDH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Fatty acid beta-oxidation using acyl-CoA dehydrogenase →	+0.150	+0.734	<.001	.007	3	13
LUNG_NSCLC_LUAD	Lipid oxidation →	+0.075	+0.706	<.001	<.001	3	10
BLOOD_Lymphoma	Vesicle tethering →	+0.079	+0.913	<.001	<.001	3	10
LARGE_INTESTINE	Copper ion export →	-0.161	-0.960	.001	.002	3	9
STOMACH	Fatty acid beta-oxidation →	+0.099	+0.707	.004	.001	2	10
LUNG_SCLC	Error-prone translesion synthesis →	+0.102	+1.049	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,805 associations by consensus.

Fatty acid beta-oxidation using acyl-CoA dehydrogenase by ETFDH expression — STOMACH

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