ETFBKMT

Across TCGA patient cohorts, ETFBKMT mutation is significantly associated with the RNA expression of many other genes, with 1,377 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ETFBKMT-associated genes across cancer lineages are RNA5SP413, RNA5SP417, and RNA5SP422. Each is linked with ETFBKMT in more than 1 cancer types. Because this analysis shows association rather than direction, both ETFBKMT-to-partner and partner-to-ETFBKMT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP413 grouped by ETFBKMT-low versus ETFBKMT-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ETFBKMT→partner) and Y-score (partner→ETFBKMT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP413 →	+0.980	+1.955	<.001	.005	3	2
UCEC	RNA5SP417 →	+0.402	+2.351	.003	.003	3	2
UCEC	RNA5SP422 →	+0.713	+2.349	<.001	.001	3	2
UCEC	RNA5SP423 →	+0.563	+2.065	.005	.005	3	2
UCEC	DOC2B →	-1.087	-2.807	.001	.003	3	1
UCEC	DCP1A →	+0.508	+2.321	.006	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,377 associations by consensus.

RNA5SP413 by ETFBKMT expression — UCEC

Explore this box plot interactively →