ETFB

Across TCGA patient cohorts, ETFB mutation is significantly associated with the RNA expression of many other genes, with 2,640 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ETFB-associated genes across cancer lineages are RN7SKP32, RNA5SP415, and USP9YP2. Each is linked with ETFB in more than 1 cancer types. Because this analysis shows association rather than direction, both ETFB-to-partner and partner-to-ETFB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP32 grouped by ETFB-low versus ETFB-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ETFB→partner) and Y-score (partner→ETFB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RN7SKP32 →	+0.110	+3.572	.005	.007	3	2
UCEC	RNA5SP415 →	+0.563	+2.266	<.001	.003	3	2
BRCA	USP9YP2 →	+0.044	+7.731	<.001	.009	3	2
SKCM	RNU7-63P →	+0.616	+4.979	<.001	.009	3	2
SKCM	RN7SL60P →	+0.155	+6.469	<.001	.001	3	2
CESC	TRAJ56 →	+0.997	+5.418	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,640 associations by consensus.

RN7SKP32 by ETFB expression — LUAD

Explore this box plot interactively →