ETFA

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ETFA protein abundance is significantly associated with the RNA expression of many other genes, with 11,089 significant associations in total. COAD shows the largest number of these associations.

The most reproducible ETFA-associated genes across cancer lineages are GLT8D2, ADAMTS4, and TAMALIN. Each is linked with ETFA in more than 4 cancer types. Because this analysis shows association rather than direction, both ETFA-to-partner and partner-to-ETFA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ETFA versus GLT8D2 in LSCC, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ETFA→partner) and Y-score (partner→ETFA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCGLT8D2 →-0.922-0.403<.001.00135
COADADAMTS4 →-0.999-0.374<.001<.00135
LSCCTAMALIN →-0.815-0.324<.001.00135
CCRCCCYTL1 →-0.683-0.192.003.00435
LUADNRIP3 →-1.152-0.316<.001<.00135
GBMTUBB →-0.651-0.362<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,089 associations by consensus.

ETFA vs GLT8D2 — LSCC

Per-sample scatter of ETFA vs GLT8D2 in LSCC (Pearson r = -0.37).

Explore this scatter interactively →

Exploration