ETDC

Across TCGA patient cohorts, ETDC RNA expression is significantly associated with the protein abundance of many other proteins, with 7,660 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible ETDC-associated proteins across cancer lineages are KANK2_S540, LRCH3_S415, and CTNNB1_S552. Each is linked with ETDC in more than 3 cancer types. Because this analysis shows association rather than direction, both ETDC-to-partner and partner-to-ETDC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ETDC versus KANK2_S540 in PDAC, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ETDC→partner) and Y-score (partner→ETDC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	KANK2_S540 →	+0.510	+0.412	.001	.001	3	4
GBM	LRCH3_S415 →	+0.513	+0.356	.001	.005	3	4
PDAC	CTNNB1_S552 →	+0.542	+0.483	.005	.004	3	4
PDAC	NUP35_S279 →	-0.746	-0.867	.007	.003	3	3
CCRCC	PRKAB2_S158 →	-0.817	-0.382	<.001	<.001	3	3
HNSC	TMX4 →	+0.350	+0.797	.005	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,660 associations by consensus.

ETDC vs KANK2_S540 — PDAC

Explore this scatter interactively →