ETDC

Across TCGA cell cohorts, ETDC RNA expression is significantly associated with the mutation status of many other genes, with 113 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ETDC-associated genes across cancer lineages are CDH11, OGFRL1, and UBR1. Each is linked with ETDC in more than 1 cancer types. Because this analysis shows association rather than direction, both ETDC-to-partner and partner-to-ETDC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CDH11 grouped by ETDC-low versus ETDC-high in LUNG_NSCLC_LUSC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ETDC→partner) and Y-score (partner→ETDC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	CDH11 →	+4.643	+0.593	.008	<.001	3	2
CNS	OGFRL1 →	+4.754	+0.725	.005	.004	3	2
CNS	UBR1 →	+4.169	+1.024	.008	<.001	3	2
LUNG_NSCLC_LUAD	COL11A2 →	+3.006	+0.217	.005	<.001	3	2
BLOOD_Lymphoma	DCDC1 →	+2.794	+0.311	.007	<.001	3	2
LUNG_NSCLC_LUSC	TEK →	+4.643	+0.593	.008	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 113 associations by consensus.

CDH11 by ETDC expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →