Across TCGA pan-cancer cohorts, ETDB RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of ETDB’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where ETDB RNA is repressed in tumor relative to normal tissue. In most cancer types ETDB is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.

LUSC are the cancer types where ETDB tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ETDB RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	−0.009	.046	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: ETDB RNA expression & survival · all ETDB data types