ETAA1

Across TCGA patient cohorts, ETAA1 mutation is significantly associated with the RNA expression of many other genes, with 3,498 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ETAA1-associated genes across cancer lineages are PIGW, MIR7845, and RNU6-1009P. Each is linked with ETAA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ETAA1-to-partner and partner-to-ETAA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PIGW grouped by ETAA1-low versus ETAA1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ETAA1→partner) and Y-score (partner→ETAA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PIGW →	+0.581	+2.711	<.001	<.001	3	2
UCEC	MIR7845 →	+0.367	+1.838	<.001	.001	3	2
LGG	RNU6-1009P →	+0.342	+5.392	<.001	.005	3	2
UCEC	ALDOA →	+0.537	+2.321	<.001	<.001	3	2
UCEC	ATP5F1A →	+0.464	+2.010	<.001	<.001	3	2
UCEC	HAUS1 →	+0.572	+2.032	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,498 associations by consensus.

PIGW by ETAA1 expression — UCEC

Explore this box plot interactively →