ETAA1

Across TCGA cell cohorts, ETAA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,934 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ETAA1-associated GO terms across cancer lineages are Regulation of DNA damage checkpoint, Negative regulation of G2/M transition of mitotic cell cycle, and Negative regulation of cell cycle G2/M phase transition. Each is linked with ETAA1 in more than 16 cancer types. Because this analysis shows association rather than direction, both ETAA1-to-partner and partner-to-ETAA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA damage checkpoint grouped by ETAA1-low versus ETAA1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ETAA1→partner) and Y-score (partner→ETAA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of DNA damage checkpoint →	+0.090	+0.866	<.001	<.001	3	17
PANCREAS	Negative regulation of G2/M transition of mitotic cell cycle →	+0.072	+0.547	<.001	.003	3	16
PANCREAS	Negative regulation of cell cycle G2/M phase transition →	+0.072	+0.546	<.001	.003	3	16
BREAST	Mitotic G2/M transition checkpoint →	+0.103	+0.777	<.001	<.001	3	15
BREAST	Negative regulation of mitotic cell cycle →	+0.071	+0.515	<.001	.002	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of G2/M transition of mitotic cell cycle →	+0.080	+0.943	.007	.001	2	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,934 associations by consensus.

Regulation of DNA damage checkpoint by ETAA1 expression — OVARY

Explore this box plot interactively →