ETAA1

Across TCGA cell cohorts, ETAA1 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ETAA1-associated genes across cancer lineages are OR1L3, C5orf52, and GALNTL5. Each is linked with ETAA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ETAA1-to-partner and partner-to-ETAA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1L3 grouped by ETAA1-low versus ETAA1-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ETAA1→partner) and Y-score (partner→ETAA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	OR1L3 →	+0.042	+4.029	<.001	.009	3	2
BLOOD_Leukemia	C5orf52 →	+0.018	+4.569	<.001	.003	3	1
LUNG_NSCLC_LUAD	GALNTL5 →	+0.069	+3.959	<.001	.001	3	1
LUNG_NSCLC_LUAD	PRLHR →	+0.040	+4.362	.003	<.001	3	1
LUNG_NSCLC_LUAD	MS4A6E →	+0.034	+4.228	<.001	<.001	3	1
LUNG_NSCLC_LUAD	PYDC1 →	+0.121	+3.343	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

OR1L3 by ETAA1 expression — OVARY

Explore this box plot interactively →