ESYT2

Across TCGA patient cohorts, ESYT2 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,798 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ESYT2-associated proteins across cancer lineages are UBE3C, CUL1, and CD109. Each is linked with ESYT2 in more than 6 cancer types. Because this analysis shows association rather than direction, both ESYT2-to-partner and partner-to-ESYT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ESYT2 versus UBE3C in OV, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ESYT2→partner) and Y-score (partner→ESYT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	UBE3C →	+0.261	+0.653	.001	.001	3	7
LSCC	CUL1 →	+0.245	+0.592	<.001	<.001	3	5
GBM	CD109 →	+0.869	+0.493	<.001	<.001	3	4
PDAC	CDH13 →	+0.428	+0.349	<.001	<.001	3	4
LSCC	FNDC3A →	-0.346	-0.397	.003	.007	3	4
GBM	S100A10 →	+0.510	+0.371	.009	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,798 associations by consensus.

ESYT2 vs UBE3C — OV

Explore this scatter interactively →