ESYT2

Across TCGA patient cohorts, ESYT2 protein abundance is significantly associated with the RNA expression of many other genes, with 12,375 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ESYT2-associated genes across cancer lineages are RHEB, UBE2H, and FAM3C. Each is linked with ESYT2 in more than 5 cancer types. Because this analysis shows association rather than direction, both ESYT2-to-partner and partner-to-ESYT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ESYT2 versus RHEB in HNSC, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ESYT2→partner) and Y-score (partner→ESYT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RHEB →	+0.573	+0.198	<.001	<.001	3	6
COAD	UBE2H →	+0.600	+0.288	<.001	<.001	3	6
HNSC	FAM3C →	+0.863	+0.229	.001	<.001	3	6
HNSC	MTPN →	+0.609	+0.237	<.001	<.001	3	5
LSCC	ATP6V1F →	+0.406	+0.196	<.001	.001	3	5
PDAC	CALU →	+0.528	+0.333	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,375 associations by consensus.

ESYT2 vs RHEB — HNSC

Explore this scatter interactively →